Invited Speaker
Koya Shimokawa
Tangle analysis of DNA catenane unlinking by the Xer/FtsK system
In 2007, Grainge et al. showed that, when coupled with FtsK, the site-specific recombinases XerC/XerD can unlink DNA catenanes and proposed a stepwise model of unlinking. Here we show that, under suitable assumptions, the proposed model is the only mathematical solution to the Xer/FtsK tangle equations. This is joint work with Mariel Vazquez and Kai Ishihara.